Table 1. Examples of cultured meat production using various types of cells and growth factors

Cells Growth factors Title References
Small satellite cells rAlbumin Simple and effective serum-free medium for sustained expansion of bovine satellite cells for cell cultured meat Stout et al. (2022)
Fish embryonic stem cells Insulin-like growth factor, Fibroblast growth factor, Transforming growth factors, Platelet-derived growth factor Toward sustainable culture media: Using artificial intelligence to optimize reduced-serum formulations for cultivated meat Nikkhah et al. (2023)
Fish embryonic stem cells Insect hydrolysate, Marine invertebrate hydrolysates Evaluating the potential of marine invertebrate and insect protein hydrolysates to reduce fetal bovine serum in cell culture media for cultivated fish production Batish et al. (2022)
Bovine myoblasts C. vulgaris extract Development of serum-free and grain-derived-nutrient-free medium using microalga-derived nutrients and mammalian cell-secreted growth factors for sustainable cultured meat production Yamanaka et al. (2023)
Bovine myoblasts C. vulgaris extract Proliferation and differentiation of primary bovine myoblasts using Chlorella vulgaris extract for sustainable production of cultured meat Okamoto et al. (2022)
Porcine muscle stem cells Fermented soybean meal, Edible insect hydrolysate Evaluation of fermented soybean meal and edible insect hydrolysates as potential serum replacement in pig muscle stem cell culture Kim et al. (2023a)
Small satellite cells Rapeseed protein isolate A Beefy-R culture medium: replacing albumin with rapeseed protein isolates Stout et al. (2023)
Mammalian cells Egg whites, Eggshell membrane, Poultry residue, Pea hydrolysate, Porcine plasma, Fibroblast growth factor Life cycle assessment of culture media with alternative compositions for cultured meat production Wali et al, (2024)
Small satellite cells Fibroblast growth factor 2 The comparison of commercial serum-free media for hanwoo satellite cell proliferation and the role of fibroblast growth factor 2 Yu et al. (2023)
Chick satellite cells Egg white extract Preliminary study on comparison of egg extraction methods for development of fetal bovine serum substitutes in cultured meat Lee et al. (2024b)
Fish satellite cells Lupin, Peas, Rapeseed, Birds, Yeast Development of serum-reduced medium for mackerel muscle cell line cultivation Lim et al. (2024)
Fish muscle cells Auxenochlorella pyrenoidosa Auxenochlorella pyrenoidosa extract supplementation replacing fetal bovine serum for Carassius auratus muscle cell culture under low-serum conditions Dong et al. (2023)
C2C12 C-phycocyanin Chitosan/cellulose-based porous nanofilm delivering C-phycocyanin: A novel platform for the production of cost-effective cultured meat Park et al. (2021b)
C2C12 Chlorococcum littorale A circular cell culture system using microalgae and mammalian myoblasts for the production of sustainable cultured meat Haraguchi et al. (2022)
C2C12Pig immortalized myoblasts Fermented okara Ultrafiltrated extracts of fermented okara as a possible serum alternative for cell culturing: potential in cultivated meat production Teng et al. (2023)
C2C12QM7 Anabaena sp. PCC 7120 Muscle cell proliferation using water-soluble extract from nitrogen-fixing cyanobacteria Anabaena sp. PCC 7120 for sustainable cultured meat production Ghosh et al. (2023)